Anti-Phospho-RGS19 (S24) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P49795
Gene Id	10287
Gene Symbols	RGS19
Protein Name / Synonyms	Phospho-RGS19(S24)
Clonality	Polyclonal
Preparation	This RGS19 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S24 of human RGS19.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Dot Blotting
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3.

Specificity

Other Names

RGS19; GAIP; GNAI3IP; Regulator of G-protein signaling 19; G-alpha-interacting protein

NCBI Accession #

NP_001034556.1;NP_005864.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

24636

Recommended Dilutions

DB: 1:500

Dot blot analysis of Phospho-RGS19-S24 Antibody (Cat# 102-15409) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products