Anti-Phospho-SQSTM1 (S403) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q13501
Gene Id	8878
Gene Symbols	SQSTM1
Protein Name / Synonyms	Phospho-SQSTM1(S403)
Clonality	Polyclonal
Preparation	This SQSTM1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S403 of human SQSTM1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Dot Blotting
Research Area	Apoptosis, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

SQSTM1; ORCA; OSIL; Sequestosome-1; EBI3-associated protein of 60 kDa; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62

NCBI Accession #

NP_001135770.1;NP_001135771.1;NP_003891.1

Other Accession #

O08623; Q64337; NP_001135770.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

47687

Recommended Dilutions

DB: 1:500

Dot blot analysis of SQSTM1 Antibody (Phospho S403) Phospho-specific Pab (Cat# 102-15660) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products