Anti-PI 4 Kinase type 2 beta (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8TCG2
Gene Id	55300
Gene Symbols	PI4K2B
Protein Name / Synonyms	PI 4 Kinase type 2 beta (N-term)
Clonality	Polyclonal
Preparation	This PI 4 Kinase type 2 beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PI 4 Kinase type 2 beta.
Concentration (lot specific)	1.360 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Phosphorylation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Specificity

Other Names

PI4K2B; Phosphatidylinositol 4-kinase type 2-beta; Phosphatidylinositol 4-kinase type II-beta

NCBI Accession #

NP_060793.2

Other Accession #

NP_060793

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

54744

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of anti-PI4K II beta Pab (Cat# 102-17769) in HL60 cell lysate. PI4K II beta (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
	Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with PI4K II beta antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with PI4K II beta antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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