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Anti-PIG3 (C-term) Antibody
Catalog #: 102-14212
Rabbit Anti-Human PIG3 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q53FA7 |
| Gene Id | 9540 |
| Gene Symbols | TP53I3 |
| Protein Name / Synonyms | PIG3 (C-term) |
| Clonality | Polyclonal |
| Preparation | This PIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3. |
| Concentration (lot specific) | 0.330 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
Specificity
Other Names
TP53I3; PIG3; Quinone oxidoreductase PIG3; Tumor protein p53-inducible protein 3; p53-induced gene 3 protein
NCBI Accession #
NP_001193731.1;NP_004872.2;NP_671713.1
Other Accession #
NP_004872.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
35536
Recommended Dilutions
WB: 1:1000
 | PIG3 Antibody (C-term)(Cat# 102-14212) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PIG3 antibody detected the PIG3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.