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Anti-Pim1 (C-term) Antibody
Catalog #: 102-21708
Rabbit Anti-Mouse Pim1 (C-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P06803 |
| Gene Id | 18712 |
| Gene Symbols | Pim1 |
| Protein Name / Synonyms | Serine/threonine-protein kinase pim-1, Pim1, Pim-1 |
| Clonality | Polyclonal |
| Clone | RB34666 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Pim1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3 (By similarity). Promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and proteasome-dependent degradation of CDKN1B (By similarity). Also represses CDKN1B transcription by phosphorylating and inactivating the transcription factor FOXO3 (By similarity). Plays a role in signal transduction in blood cells (By similarity). Contributes to both cell proliferation and survival thus providing a selective advantage in tumorigenesis (By similarity).
Other Information
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
35451
Antigen Source
Mouse
Images
WB (1:1000)
Mouse Pim1 Antibody (C-term) (Cat. #102-21708) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the Pim1 antibody detected the Pim1 protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.