Anti-PKM2 Antibody

Product Description

Specifications

Size	100 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Mouse
Accession Number	P14618
Gene Id	5315
Gene Symbols	PKM
Protein Name / Synonyms	CTHBP ;Cytosolic thyroid hormone binding protein ;Cytosolic thyroid hormone-binding protein ;KPYM_HUMAN ;MGC3932 ;OIP 3 ;OIP-3 ;OIP3 ;OPA interacting protein 3 ;Opa-interacting protein 3 ;p58 ;PK muscle type ;PK, muscle type ;PK2 ;PK3 ;PKM ;PKM2 ;pykm ;Pyruvate kinase 2/3 ;Pyruvate kinase 3 ;Pyruvate kinase isozymes M1/M2 ;Pyruvate kinase muscle ;Pyruvate kinase muscle isozyme ;pyruvate kinase PKM ;Pyruvate kinase, muscle 2 ;TCB ;THBP1 ;Thyroid hormone binding protein 1 ;Thyroid hormone binding protein cytosolic ;Thyroid hormone-binding protein 1 ;Tumor M2 PK ;Tumor M2-PK .
Clonality	Monoclonal
Recommended Applications	Western Blotting
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

Other Information

Antigen Type

Recombinant Protein

Images

WB (1:1000)

Western blot detection of PKM2 in HCT116,COS7,K562,A549 and Hela cell lysates using PKM2 mouse mAb (1:1000 diluted).Predicted band size:60KDa.Observed band size:60KDa.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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