Anti-POLR1C (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O15160
Gene Id	9533
Gene Symbols	POLR1C
Protein Name / Synonyms	POLR1C (C-term)
Clonality	Polyclonal
Preparation	This POLR1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-346 amino acids from the C-terminal region of human POLR1C.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

Specificity

Other Names

POLR1C; POLR1E; DNA-directed RNA polymerases I and III subunit RPAC1; AC40; DNA-directed RNA polymerases I and III 40 kDa polypeptide; RPA39; RPC40

NCBI Accession #

NP_976035.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

39250

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of anti-POLR1C Antibody (C-term) (Cat# 102-15176) in A2058 cell line lysates (35ug/lane). POLR1C (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with POLR1C antibody (C-term) (Cat# 102-15176), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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