Rabbit Anti-Human PON1 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P27169 |
| Gene Id | 5444 |
| Gene Symbols | PON1 |
| Protein Name / Synonyms | PON1 (Center) |
| Clonality | Polyclonal |
| Preparation | This PON1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human PON1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC, IHC-P |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
Specificity
Other Names
PON1; PON; Serum paraoxonase/arylesterase 1; Aromatic esterase 1; K-45; Serum aryldialkylphosphatase 1
NCBI Accession #
NP_000437.3
Other Accession #
NP_000437.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39731
Recommended Dilutions
WB: 1:1000; FC: 1:10-50; IHC: 1:10-50
 | Western blot analysis of lysate from human blood plasma tissue lysate, using PON1 Antibody (Center)(Cat# 102-10756). 102-10756 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. |
 | PON1 Antibody (Center) (Cat# 102-10756) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
 | PON1 Antibody (Center) (Cat# 102-10756)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PON1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.