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Anti-PPM1F (Center) Antibody
Catalog #: 102-14495
Rabbit Anti-Human PPM1F (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49593 |
| Gene Id | 9647 |
| Gene Symbols | PPM1F |
| Protein Name / Synonyms | PPM1F (Center) |
| Clonality | Polyclonal |
| Preparation | This PPM1F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the Central region of human PPM1F. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.
Specificity
Other Names
PPM1F; KIAA0015; POPX2; Protein phosphatase 1F; Ca(2+)/calmodulin-dependent protein kinase phosphatase; Partner of PIX 2; Protein fem-2 homolog
NCBI Accession #
NP_055449.1
Other Accession #
NP_055449.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
49831
Recommended Dilutions
WB: 1:1000
 | PPM1F Antibody (Center) (Cat# 102-14495) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the PPM1F antibody detected the PPM1F protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.