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Anti-Prekallikrein (Heavy Chain) Antibody
Catalog #: MD-20-0052
Mouse Anti-Plasminogen / Angiostatin/ PLG (200 ug)
Product Description
Specifications
| Size | 200 µg |
| Estimated Lead Time | 3-4 weeks |
| Host Species | Mouse |
| Protein Name / Synonyms | Plasminogen / Angiostatin/ PLG |
| Concentration (lot specific) | Lot Specific, Approx. 0.6 mg/ml (as determined by OD280 nm) |
| Recommended Applications | Suitable for use in ELISA and Western blot. |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Specificity
Recognizes two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha -2-macroglobulin and Antithrombin III, and 45 kDa p rekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
Storage/Stability
Upon receipt, aliquot and store at -20 °C. Avoid multiple freeze/thaw cycles.
More Information
Immunogen
Purified human plasma prekallikrein
Format Type:
Purified Liquid
Formulation:
PBS, pH 7.4
Expiration:
12 months from the date of shipment when stored properly.