3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-PRELP (Center) Antibody
Catalog #: 102-16879
Rabbit Anti-Human PRELP (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P51888 |
| Gene Id | 5549 |
| Gene Symbols | PRELP |
| Protein Name / Synonyms | PRELP (Center) |
| Clonality | Polyclonal |
| Preparation | This PRELP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human PRELP. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
Specificity
Other Names
PRELP; SLRR2A; Prolargin; Proline-arginine-rich end leucine-rich repeat protein
NCBI Accession #
NP_002716.1;NP_958505.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
43810
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | PRELP Antibody (Center) (Cat# 102-16879) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the PRELP antibody detected PRELP protein (arrow). |
 | PRELP Antibody (Center) (Cat# 102-16879) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRELP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.