Anti-PRKAA1 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	Q13131
Gene Id	5562
Gene Symbols	PRKAA1
Protein Name / Synonyms	PRKAA1
Clonality	Monoclonal
Preparation	This PRKAA1 monoclonal antibody is generated from mouse immunized with PRKAA1 recombinant protein.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.

Specificity

Predicted Reactivity

Rat

Other Names

PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; Acetyl-CoA carboxylase kinase; Hydroxymethylglutaryl-CoA reductase kinase; Tau-protein kinase PRKAA1

NCBI Accession #

NP_006242.5;NP_996790.3

Other Accession #

P54645; NP_006242.5

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

64009

Recommended Dilutions

WB: 1:100-500

PRKAA1 Antibody (Cat# 102-10083) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PRKAA1 antibody detected the PRKAA1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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