Anti-PRL3 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O75365
Gene Id	11156
Gene Symbols	PTP4A3
Protein Name / Synonyms	PRL3 (C-term)
Clonality	Polyclonal
Preparation	This PRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the C-terminal region of human PRL3.
Concentration (lot specific)	2.000 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

Specificity

Predicted Reactivity

Mouse, Bovine

Other Names

PTP4A3; PRL3; Protein tyrosine phosphatase type IVA 3; PRL-R; Protein-tyrosine phosphatase 4a3; Protein-tyrosine phosphatase of regenerating liver 3

NCBI Accession #

NP_009010.2;NP_116000.1

Other Accession #

Q9D658; A2VDT1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

19535

Recommended Dilutions

WB: 1:1000

Western blot analysis of PTP4A3 C-term (Cat# 102-17875) in MCF-7 and 293 cell line lysates (35ug/lane). PTP4A3 (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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