Anti-PTPRE (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P23469
Gene Id	5791
Gene Symbols	PTPRE
Protein Name / Synonyms	PTPRE (N-term)
Clonality	Polyclonal
Preparation	This PTPRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE.
Concentration (lot specific)	0.480 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq].

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

PTPRE; Receptor-type tyrosine-protein phosphatase epsilon

NCBI Accession #

NP_006495.1;NP_569119.1

Other Accession #

B2GV87; P49446; NP_569119.1; NP_006495.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

80642

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	PTPRE Antibody (N-term) (Cat# 102-12472) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PTPRE antibody detected the PTPRE protein (arrow).
	PTPRE Antibody (N-term) (102-12472)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPRE Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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