Anti-PTPRN (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q16849
Gene Id	5798
Gene Symbols	PTPRN
Protein Name / Synonyms	PTPRN (Center)
Clonality	Polyclonal
Preparation	This PTPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PTPRN.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.

Specificity

Other Names

PTPRN; ICA3; ICA512; Receptor-type tyrosine-protein phosphatase-like N; Islet cell antigen 512; Islet cell autoantigen 3; PTP IA-2

NCBI Accession #

NP_001186692.1;NP_001186693.1;NP_002837.1

Other Accession #

NP_002837.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

105848

Recommended Dilutions

WB: 1:1000

PTPRN Antibody (Center) (Cat# 102-12524) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PTPRN antibody detected the PTPRN protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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