RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-pTyr Antibody, HRP

Catalog #: DS-MB-02121

Mouse Anti-pTyr [+HRP]

Product Description

Specifications

Size0.5 mL
Estimated Lead Time1-2 weeks
Specificity
This product recognizes phosphotyrosine, enabling the detection, characterisation and isolation of proteins containing phosphorylated tyrosine residues.

The phosphorylation of tyrosine acts as a important signal in the control of cell mitogenesis, differentiation, proliferation, and migration and occurs following the activation of intracellular tyrosine kinases, including the T-cell receptor (TCR), epidermal growth factor (EGF) and many families of receptor and non-receptor protein tyrosine kinases (PTKs), which catalyse the transfer of ATP to a tyrosine residue on specific cell protein targets.

The binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate, but not by free phosphate, phosphoserine or phosphothreonine.

The affinity for phosphotyrosine is 10-6 to 10-7 M.
Host SpeciesMouse
Protein Name / Synonyms
pTyr
Recommended ApplicationsELISA (dilution: 1/1000 , 1/4000)
Shipping TypeBlue ice
Storage-20°C

Description

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
Formulation:
Phosphate buffered saline

Preparation

Preservative:
0.01% Thiomersal
50% Glycerol
Expiration:
12 months from the date of shipment when stored properly.