Anti-PUF60 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9UHX1
Gene Id	22827
Gene Symbols	PUF60
Protein Name / Synonyms	PUF60 (N-term)
Clonality	Polyclonal
Preparation	This PUF60 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human PUF60.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Specificity

Other Names

PUF60; FIR; ROBPI; SIAHBP1; Poly(U)-binding-splicing factor PUF60; 60 kDa poly(U)-binding-splicing factor; FUSE-binding protein-interacting repressor; Ro-binding protein 1; Siah-binding protein 1

NCBI Accession #

NP_001129505.1;NP_001258025.1;NP_001258026.1;NP_001258027.1;NP_001258028.1;NP_001258029.1;NP_055096.2;NP_510965.1

Other Accession #

NP_510965.1; NP_055096.2; NP_001129505.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

59875

Recommended Dilutions

WB: 1:1000

PUF60 Antibody (N-term) (Cat# 102-12457) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PUF60 antibody detected the PUF60 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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