Anti-PURA (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q00577
Gene Id	5813
Gene Symbols	PURA
Protein Name / Synonyms	PURA (C-term)
Clonality	Polyclonal
Preparation	This PURA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the C-terminal region of human PURA.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	IHC-P, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Specificity

Predicted Reactivity

Mouse

Other Names

PURA; PUR1; Transcriptional activator protein Pur-alpha; Purine-rich single-stranded DNA-binding protein alpha

NCBI Accession #

NP_005850.1

Other Accession #

P42669; NP_005850.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

34911

Recommended Dilutions

IHC: 1:50-100; WB: 1:1000

	PURA Antibody (C-term) (Cat# 102-11257)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PURA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	PURA Antibody (C-term) (Cat# 102-11257) western blot analysis in A549,NCI-H292 cell line lysates (35ug/lane).This demonstrates the PURA antibody detected the PURA protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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