Anti-PVR (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P15151
Gene Id	5817
Gene Symbols	PVR
Protein Name / Synonyms	PVR (C-term)
Clonality	Polyclonal
Preparation	This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names

PVR; PVS; Poliovirus receptor; Nectin-like protein 5; CD_antigen=CD155; Flags: Precursor

NCBI Accession #

NP_001129240.1;NP_001129241.1;NP_001129242.1;NP_006496.3

Other Accession #

NP_006496.3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

45303

Recommended Dilutions

WB: 1:1000

PVR Antibody (C-term) (Cat# 102-14505) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PVR antibody detected the PVR protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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