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Anti-Pyruvate Kinase (PKM2) (N-term) Antibody
Catalog #: 102-17096
Rabbit Anti-Pyruvate Kinase (PKM2) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P14618 |
| Gene Id | 5315 |
| Gene Symbols | PKM |
| Protein Name / Synonyms | Pyruvate Kinase (PKM2) (N-term) |
| Clonality | Polyclonal |
| Preparation | This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-151 amino acids from the N-terminal region of human Pyruvate Kinase (PKM2). |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Phosphorylation, Energy Metabolism, Glycolysis & Lipid Metabolism |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Specificity
Predicted Reactivity
Rat, Rabbit
Other Names
PKM; OIP3; PK2; PK3; PKM2; Pyruvate kinase isozymes M1/M2; Cytosolic thyroid hormone-binding protein; Opa-interacting protein 3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Tumor M2-PK; p58
NCBI Accession #
NP_001193725.1;NP_001193726.1;NP_001193727.1;NP_001193728.1;NP_002645.3;NP_872270.1;NP_872271.1
Other Accession #
P11980; P11974; P52480; P14786
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
57937
Recommended Dilutions
WB: 1:1000
 | The anti-PKM2 Pab (Cat# 102-17096) is used in Western blot to detect PKM2 in HeLa cell lysate (Lane 1) and 3T3 cell lysate (Lane 2). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.