Anti-QPRT (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q15274
Gene Id	23475
Gene Symbols	QPRT
Protein Name / Synonyms	QPRT (C-term)
Clonality	Polyclonal
Preparation	This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Specificity

Other Names

QPRT; Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Quinolinate phosphoribosyltransferase [decarboxylating]

NCBI Accession #

NP_055113.2

Other Accession #

NP_055113.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

30846

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	QPRT Antibody (C-term) (Cat# 102-12463) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the QPRT antibody detected the QPRT protein (arrow).
	QPRT Antibody (C-term) (102-12463)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of QPRT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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