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Anti-RAB7A Antibody
Catalog #: 144-62075
RAB7A pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P51149 |
| Gene Id | 7879 |
| Gene Symbols | RAB7A |
| Protein Name / Synonyms | RAB7A, PRO2706, RAB7, ras-related protein Rab-7a |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Dilutions
WB 1:500 - 1:2000; IHC 1:10 - 1:100
Format
Calculated MW
23kDa
Observed MW
23kDa
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RAB7A (NP_004628.4).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.