Anti-RASSF1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q9NS23
Gene Id	11186
Gene Symbols	RASSF1
Protein Name / Synonyms	RASSF1 (Center)
Clonality	Polyclonal
Preparation	This RASSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human RASSF1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Specificity

Other Names

RASSF1; RDA32; Ras association domain-containing protein 1

NCBI Accession #

NP_001193886.1;NP_009113.3;NP_733830.1;NP_733831.1;NP_733832.1

Other Accession #

NP_009113.3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

39219

Recommended Dilutions

WB: 1:1000

RASSF1 Antibody (Center) (Cat# 102-13576) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the RASSF1 antibody detected the RASSF1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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