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Anti-Rat Phospho-rat TSC1 (S1141) Antibody
Catalog #: 102-15686
Rabbit Anti-Rat Phospho-rat TSC1(S1141) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Rat |
| Host Species | Rabbit |
| Accession Number | Q9Z136 |
| Gene Id | 60445 |
| Gene Symbols | TSC1 |
| Protein Name / Synonyms | Rat Phospho-rat TSC1(S1141) |
| Clonality | Polyclonal |
| Preparation | This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1141 of rat TSC1. |
| Concentration (lot specific) | 0.280 mg/ml |
| Recommended Applications | Dot Blotting |
| Research Area | Cardiovascular Disease, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Specificity
Other Names
Tsc1; Hamartin; Tuberous sclerosis 1 protein homolog
NCBI Accession #
NP_068626.1
Other Accession #
NP_068626.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
129022
Recommended Dilutions
DB: 1:500
 | Dot blot analysis of rat TSC1 Antibody (Phospho S1141) Phospho-specific Pab (Cat# 102-15686) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
Antigen Source
RAT
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.