Rabbit Anti-Human RENT1 (N-term E22) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q92900 |
| Gene Id | 5976 |
| Gene Symbols | UPF1 |
| Protein Name / Synonyms | RENT1 (N-term E22) |
| Clonality | Polyclonal |
| Preparation | This RENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 amino acids from the N-terminal region of human RENT1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.
Specificity
Predicted Reactivity
Mouse
Other Names
UPF1; KIAA0221; RENT1; Regulator of nonsense transcripts 1; ATP-dependent helicase RENT1; Nonsense mRNA reducing factor 1; Up-frameshift suppressor 1 homolog
NCBI Accession #
NP_002902.2
Other Accession #
Q9EPU0
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
124345
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of RENT1 (arrow) using rabbit polyclonal RENT1 Antibody (N-term E22) (Cat# 102-14121). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RENT1 gene (Lane 2) (Origene Technologies). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.