Anti-RFXAP (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O00287
Gene Id	5994
Gene Symbols	RFXAP
Protein Name / Synonyms	RFXAP (C-term)
Clonality	Polyclonal
Preparation	This RFXAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human RFXAP.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.

Specificity

Predicted Reactivity

Mouse

Other Names

RFXAP; Regulatory factor X-associated protein; RFX DNA-binding complex 36 kDa subunit

NCBI Accession #

NP_000529.1

Other Accession #

Q8VCG9; NP_000529.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

28232

Recommended Dilutions

WB: 1:1000

RFXAP Antibody (C-term) (Cat# 102-12516) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RFXAP antibody detected the RFXAP protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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