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Anti-RGS1 (N-term) Antibody
Catalog #: 102-18017
Rabbit Anti-Human RGS1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q08116 |
| Gene Id | 5996 |
| Gene Symbols | RGS1 |
| Protein Name / Synonyms | RGS1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This RGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human RGS1. |
| Concentration (lot specific) | 0.471 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Specificity
Other Names
RGS1; 1R20; BL34; IER1; Regulator of G-protein signaling 1; B-cell activation protein BL34; Early response protein 1R20
NCBI Accession #
NP_002913.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23858
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of RGS1 Antibody (N-term) (Cat# 102-18017) in HL-60 cell line lysates (35ug/lane). RGS1 (arrow) was detected using the purified Pab. |
 | RGS1 Antibody (N-term) (Cat# 102-18017) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.