Anti-RGS19 (S151) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P49795
Gene Id	10287
Gene Symbols	RGS19
Protein Name / Synonyms	RGS19 (S151)
Clonality	Polyclonal
Preparation	This RGS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-156 amino acids from human RGS19.
Concentration (lot specific)	0.380 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

Specificity

Predicted Reactivity

Rat, Bovine

Other Names

RGS19; GAIP; GNAI3IP; Regulator of G-protein signaling 19; G-alpha-interacting protein

NCBI Accession #

NP_001034556.1;NP_005864.1

Other Accession #

O70521; Q9CX84; Q08DC7

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

24636

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of anti-RGS19 Antibody (S151) (Cat# 102-13728) in mouse muscle tissue lysates (35ug/lane). RGS19(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Phospho-RGS19-pS151.ctrl antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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