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Anti-RGS4 (Center) Antibody
Catalog #: 102-18064
Rabbit Anti-RGS4 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P49798 |
| Gene Id | 5999 |
| Gene Symbols | RGS4 |
| Protein Name / Synonyms | RGS4 (Center) |
| Clonality | Polyclonal |
| Preparation | This RGS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the Central region of human RGS4. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
Specificity
Predicted Reactivity
Rat, Bovine, Monkey, Rabbit
Other Names
RGS4; Regulator of G-protein signaling 4
NCBI Accession #
NP_001095915.1;NP_001106851.1;NP_001106852.1;NP_005604.1
Other Accession #
P49799; Q0R4E4; Q4R525; Q29RM9
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23256
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of RGS4 Antibody (Center) (Cat# 102-18064) in MDA-MB231 cell line lysates (35ug/lane). RGS4 (arrow) was detected using the purified Pab. |
 | Western blot analysis of RGS4 Antibody (Center) (Cat# 102-18064) in mouse brain tissue lysates (35ug/lane). RGS4 (arrow) was detected using the purified Pab. |
 | Western blot analysis of RGS4 (arrow) using rabbit polyclonal RGS4 Antibody (Center) (Cat# 102-18064). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RGS4 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.