Rabbit Anti-Human RHEB (C-term) Antibody, 400 ul
Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15382 |
| Gene Id | 6009 |
| Gene Symbols | RHEB |
| Protein Name / Synonyms | RHEB (C-term) |
| Clonality | Polyclonal |
| Preparation | This RHEB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-134 amino acids from the C-terminal region of human RHEB. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
RHEB; RHEB2; GTP-binding protein Rheb; Ras homolog enriched in brain
NCBI Accession #
NP_005605.1
Other Accession #
Q62639; Q921J2; Q56JV3; NP_005605.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
20497
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | RHEB Antibody (C-term) (Cat# 102-11244) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RHEB antibody detected the RHEB protein (arrow). |
 | RHEB Antibody (C-term) (Cat# 102-11244)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHEB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.