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Anti-RIPK3 (Center) Antibody
Catalog #: 102-17166
Rabbit Anti-RIPK3 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9Y572 |
| Gene Id | 11035 |
| Gene Symbols | RIPK3 |
| Protein Name / Synonyms | RIPK3 (Center) |
| Clonality | Polyclonal |
| Preparation | This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-91 amino acids from the Central region of human RIPK3. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Specificity
Other Names
RIPK3; RIP3; Receptor-interacting serine/threonine-protein kinase 3; RIP-like protein kinase 3; Receptor-interacting protein 3
NCBI Accession #
NP_006862.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
56887
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of RIP3 (RIPK3) Antibody (Center) (Cat# 102-17166) in Hela cell line lysates (35ug/lane). RIPK3 (arrow) was detected using the purified Pab. |
 | Western blot analysis of RIP3 (RIPK3) Antibody (Center) (Cat# 102-17166) in mouse cerebellum tissue lysates (35ug/lane). RIPK3 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with RIP3 (RIPK3) antibody (Center) (Cat# 102-17166), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.