RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-RNF14 (C-term) Antibody

Catalog #: 102-13489

Rabbit Anti-Human RNF14 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9UBS8
Gene Id
9604
Gene Symbols
RNF14
Protein Name / Synonyms
RNF14 (C-term)
ClonalityPolyclonal
PreparationThis RNF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the C-terminal region of human RNF14.
Concentration (lot specific)
0.450 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Specificity

Other Names
RNF14; ARA54; E3 ubiquitin-protein ligase RNF14; Androgen receptor-associated protein 54; HFB30; RING finger protein 14; Triad2 protein
NCBI Accession #
NP_001188294.1;NP_004281.1;NP_899645.1;NP_899646.1;NP_899647.1;NP_899648.1
Other Accession #
NP_899646.1; NP_004281.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
53837
Recommended Dilutions
WB: 1:1000
RNF14 Antibody (C-term) (Cat# 102-13489) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RNF14 antibody detected the RNF14 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.