Anti-RNH1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P13489
Gene Id	6050
Gene Symbols	RNH1
Protein Name / Synonyms	RNH1 (C-term)
Clonality	Polyclonal
Preparation	This RNH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 425-454 amino acids from the C-terminal region of human RNH1.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting, IF
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

Specificity

Other Names

RNH1; PRI; RNH; Ribonuclease inhibitor; Placental ribonuclease inhibitor; Ribonuclease/angiogenin inhibitor 1

NCBI Accession #

NP_002930.2;NP_976317.1;NP_976318.1;NP_976319.1;NP_976320.1;NP_976321.1;NP_976322.1;NP_976323.1

Other Accession #

NP_976318.1; NP_976317.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

49973

Recommended Dilutions

WB: 1:1000; IF: 1:10-50

	Western blot analysis of lysate from HT29 cell line,using RNH1 Antibody (C-term)(Cat# 102-11564).102-11564 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane.
	Confocal immunofluorescent analysis of RNH1 Antibody (C-term) (Cat# 102-11564) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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