3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-RPA1 (C-term) Antibody
Catalog #: 102-12477
Rabbit Anti-Human RPA1 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P27694 |
| Gene Id | 6117 |
| Gene Symbols | RPA1 |
| Protein Name / Synonyms | RPA1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This RPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the C-terminal region of human RPA1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Specificity
Other Names
RPA1; REPA1; RPA70; Replication protein A 70 kDa DNA-binding subunit; Replication factor A protein 1; Single-stranded DNA-binding protein
NCBI Accession #
NP_002936.1
Other Accession #
NP_002936.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
68138
Recommended Dilutions
WB: 1:1000
 | RPA1 Antibody (C-term) (Cat# 102-12477) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RPA1 antibody detected the RPA1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.