Anti-RRM2B (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q7LG56
Gene Id	50484
Gene Symbols	RRM2B
Protein Name / Synonyms	RRM2B (Center)
Clonality	Polyclonal
Preparation	This RRM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human RRM2B.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Specificity

Predicted Reactivity

Mouse, Monkey

Other Names

RRM2B; P53R2; Ribonucleoside-diphosphate reductase subunit M2 B; TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein

NCBI Accession #

NP_001165948.1;NP_001165949.1;NP_056528.2

Other Accession #

Q6PEE3; Q4R741; NP_001165948.1; NP_001165949.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

40737

Recommended Dilutions

WB: 1:1000

RRM2B Antibody (Center) (Cat# 102-13250) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RRM2B antibody detected the RRM2B protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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