Anti-RSK2 (RPS6KA3) (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P51812
Gene Id	6197
Gene Symbols	RPS6KA3
Protein Name / Synonyms	RSK2 (RPS6KA3) (N-term)
Clonality	Polyclonal
Preparation	This RSK2 (RPS6KA3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human RSK2 (RPS6KA3).
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

RSK3 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).

Specificity

Other Names

RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 kinase alpha-3; 90 kDa ribosomal protein S6 kinase 3; Insulin-stimulated protein kinase 1; MAP kinase-activated protein kinase 1b; Ribosomal S6 kinase 2; pp90RSK2

NCBI Accession #

NP_004577.1

Other Accession #

P18654

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

83736

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	RSK3 Antibody (N-term) (Cat# 102-17714) western blot analysis in Ramos cell line and mouse thymus tissue lysates (35ug/lane).This demonstrates the RSK3 antibody detected the RSK3 protein (arrow).
	Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with RSK3 antibody (N-term) (Cat# 102-17714), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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