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Anti-S100P Antibody, Biotinylated
Catalog #: 130-10036B-50
Rabbit anti-S100P Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P25815 |
| Gene Id | 6286 |
| Gene Symbols | S100P S100E |
| Clonality | Polyclonal |
| Immunogen | Immunogen was recombinant protein derived from Human S100P. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbitt serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography. |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1: 80, 000(at least detecting 12.5 µg/ml)) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
S100 calcium-binding protein P (S100P) is one member of S100 family and shares 50% sequence identity with human S100A1 and 44% identity with S100B. S100P contains 2 EF-hands (calcium binding domains) with different affinities for Ca2+, Zn2+ and Mg2+, a central hinge region and the Cterminal extension. S100P presents in various normal tissues (such as lung, placenta, kidney, heart, bladder, spleen, bone marrow, prostate gland, and intestinal mucosa), malignant tissues (such as non-small-cell lung cancer, melanoma, gastric adenocarcinoma, ovarian, breast, colon and prostate carcinoma), and the body fluids (such as blood, pancreatic juice, tear, and urine).
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
The antibody can specifically bind to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse and rat S100P has not yet been tested.
Related Products
Recombinant Human S100P (cat#230-00031)Recombinant Human S100 Calcium Binding Protein P(cat#230-00031-3)
References
- Donato R. S100: a multigenic family of calciummodulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol.2001. 33(7): 637-68.
- Basu GD, et al. Functional evidence implicating S100P in prostate cancer progression. Int J Cancer.2008. 15;123(2):330-9.
Expiration:
12 months from the date of shipment when stored properly.