Anti-SCP2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P22307
Gene Id	6342
Gene Symbols	SCP2
Protein Name / Synonyms	SCP2 (N-term)
Clonality	Polyclonal
Preparation	This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human SCP2.
Concentration (lot specific)	0.490 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Specificity

Other Names

SCP2; Non-specific lipid-transfer protein; Propanoyl-CoA C-acyltransferase; SCP-chi; SCPX; Sterol carrier protein 2; Sterol carrier protein X

NCBI Accession #

NP_001007099.1;NP_001007100.1;NP_001007101.1;NP_001007251.1;NP_001180528.1;NP_001180546.1;NP_002970.2

Other Accession #

NP_001007101.1; NP_001007251.1; NP_001007100.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

58994

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	SCP2 Antibody (N-term) (Cat# 102-11606) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the SCP2 antibody detected the SCP2 protein (arrow).
	SCP2 Antibody (N-term) (Cat# 102-11606)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SCP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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