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Anti-SDC2 Antibody
Catalog #: 144-01810
SDC2 Polyclonal Antibody
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P34741 |
| Gene Id | 6383 |
| Gene Symbols | SDC2 |
| Protein Name / Synonyms | SDC2, CD362, HSPG, HSPG1, SYND2, syndecan-2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IHC 1:50 - 1:100
Format
Calculated MW
22kDa
Observed MW
50kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human SDC2 (NP_002989.2).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of HeLa cells, using SDC2 antibody (144-01810) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded mouse lung using SDC2 antibody (144-01810) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver injury using SDC2 antibody (144-01810) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using SDC2 antibody (144-01810) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using SDC2 antibody (144-01810) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using SDC2 antibody (144-01810) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.