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Anti-SENP3 (N-term) Antibody

Catalog #: 102-11521

Rabbit Anti-Human SENP3 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9H4L4
Gene Id
26168
Gene Symbols
SENP3
Protein Name / Synonyms
SENP3 (N-term)
ClonalityPolyclonal
PreparationThis SENP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SENP3.
Concentration (lot specific)
2.0 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

SENP3 releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. This protein deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.

Specificity

Predicted Reactivity
Mouse
Other Names
SENP3; SSP3; SUSP3; Sentrin-specific protease 3; SUMO-1-specific protease 3; Sentrin/SUMO-specific protease SENP3
NCBI Accession #
NP_056485.2
Other Accession #
Q9EP97

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
65010
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
Western blot analysis of SENP3 N-term polyclonal antibody (Cat# 102-11521) in Saos-2 cell lysate. SENP3 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with SENP3 antibody (N-term) (Cat# 102-11521), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.