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Anti-SERPINB8 (C-term) Antibody
Catalog #: 102-14533
Rabbit Anti-Human SERPINB8 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P50452 |
| Gene Id | 5271 |
| Gene Symbols | SERPINB8 |
| Protein Name / Synonyms | SERPINB8 (C-term) |
| Clonality | Polyclonal |
| Preparation | This SERPINB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-301 amino acids from the C-terminal region of human SERPINB8. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).
Specificity
Other Names
SERPINB8; PI8; Serpin B8; Cytoplasmic antiproteinase 2; Peptidase inhibitor 8
NCBI Accession #
NP_001027018.1;NP_001263419.1;NP_002631.3;NP_942130.1
Other Accession #
NP_002631.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42767
Recommended Dilutions
WB: 1:1000
 | SERPINB8 Antibody (C-term) (Cat# 102-14533) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SERPINB8 antibody detected the SERPINB8 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.