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Anti-SERPINE1 (Center) Antibody
Catalog #: 102-11792
Rabbit Anti-Human SERPINE1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P05121 |
| Gene Id | 5054 |
| Gene Symbols | SERPINE1 |
| Protein Name / Synonyms | SERPINE1 (Center) |
| Clonality | Polyclonal |
| Preparation | This SERPINE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human SERPINE1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Angiogenesis, Cardiovascular Disease, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specificity
Other Names
SERPINE1; PAI1; PLANH1; Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; Serpin E1
NCBI Accession #
NP_000593.1
Other Accession #
NP_000593.1; NP_001158885.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
45060
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of SERPINE1 (arrow) using rabbit polyclonal SERPINE1 Antibody (Center) (Cat# 102-11792). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SERPINE1 gene. |
 | SERPINE1 Antibody (Center) (Cat# 102-11792) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.