Anti-Sestrin-3 (Center Y335) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P58005
Gene Id	143686
Gene Symbols	SESN3
Protein Name / Synonyms	Sestrin-3 (Center Y335)
Clonality	Polyclonal
Preparation	This Sestrin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the Central region of human Sestrin-3.
Concentration (lot specific)	0.299 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice.

Specificity

Predicted Reactivity

Mouse

Other Names

SESN3; SEST3; Sestrin-3

NCBI Accession #

NP_653266.2

Other Accession #

Q9CYP7; NP_653266.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

57291

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Sestrin-3 Antibody (Center Y335) (Cat# 102-11584) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Sestrin-3 antibody detected the Sestrin-3 protein (arrow).
	Sestrin-3 Antibody (Center Y335) (Cat# 102-11584)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Sestrin-3 Antibody (Center Y335) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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