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Anti-SF3B2 (Center) Antibody

Catalog #: 102-12892

Rabbit Anti-Human SF3B2 (Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q13435
Gene Id
10992
Gene Symbols
SF3B2
Protein Name / Synonyms
SF3B2 (Center)
ClonalityPolyclonal
PreparationThis SF3B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-568 amino acids from the Central region of human SF3B2.
Concentration (lot specific)
0.440 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq].

Specificity

Other Names
SF3B2; SAP145; Splicing factor 3B subunit 2; Pre-mRNA-splicing factor SF3b 145 kDa subunit; SF3b150; Spliceosome-associated protein 145
NCBI Accession #
NP_006833.2
Other Accession #
NP_006833.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
100228
Recommended Dilutions
WB: 1:1000
SF3B2 Antibody (Center) (Cat# 102-12892) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SF3B2 antibody detected the SF3B2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.