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Anti-SHMT1 (N-term) Antibody
Catalog #: 102-12482
Rabbit Anti-Human SHMT1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P34896 |
| Gene Id | 6470 |
| Gene Symbols | SHMT1 |
| Protein Name / Synonyms | SHMT1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SHMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human SHMT1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Specificity
Predicted Reactivity
Bovine
Other Names
SHMT1; Serine hydroxymethyltransferase, cytosolic; Glycine hydroxymethyltransferase; Serine methylase
NCBI Accession #
NP_004160.3;NP_683718.1
Other Accession #
Q5E9P9; NP_004160.3; NP_683718.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
53083
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | SHMT1 Antibody (N-term) (Cat# 102-12482) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SHMT1 antibody detected the SHMT1 protein (arrow). |
 | SHMT1 Antibody (N-term) (102-12482)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SHMT1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.