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Anti-SIGLEC5 (N-term) Antibody
Catalog #: 102-13077
Rabbit Anti-Human SIGLEC5 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O15389 |
| Gene Id | 8778 |
| Gene Symbols | SIGLEC5 |
| Protein Name / Synonyms | SIGLEC5 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SIGLEC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the N-terminal region of human SIGLEC5. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The sialic acid-binding immunoglobulin-like lectins (SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin (Ig) superfamily that mediate protein-carbohydrate interactions. They specifically interact with sialic acids in glycoproteins and glycolipids, with each SIGLEC having a particular preference for both the nature of the sialic acid and its glycosidic linkage to adjacent sugars. SIGLECs have similar structures, including extracellular Ig-like domains composed of an N-terminal V-set domain followed by varying numbers of C2-set domains. It appears that all SIGLECs have an unusual arrangement of conserved cysteine residues in the V-set and adjacent C2-set domains. Most SIGLECs are expressed uniquely within the hematopoietic system (Cornish et al., 1998 [PubMed 9731071]).
Specificity
Other Names
SIGLEC5; CD33L2; OBBP2; Sialic acid-binding Ig-like lectin 5; CD33 antigen-like 2; Obesity-binding protein 2; CD_antigen=CD170; Flags: Precursor
NCBI Accession #
NP_003821.1
Other Accession #
Q08ET2; NP_003821.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
60715
Recommended Dilutions
WB: 1:1000
 | SIGLEC5 Antibody (N-term) (Cat# 102-13077) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SIGLEC5 antibody detected the SIGLEC5 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.