Anti-SILV (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P40967
Gene Id	6490
Gene Symbols	PMEL
Protein Name / Synonyms	SILV (Center)
Clonality	Polyclonal
Preparation	This SILV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 412-440 amino acids from the Central region of human SILV.
Concentration (lot specific)	0.300 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Specificity

Other Names

PMEL; D12S53E; PMEL17; SILV; Melanocyte protein PMEL; ME20-M; Melanocyte protein Pmel 17; Melanocytes lineage-specific antigen GP100; Melanoma-associated ME20 antigen; P1; P100; Premelanosome protein; Silver locus protein homolog; M-alpha; 95 kDa melanocyte-specific secreted glycoprotein; P26; Secreted melanoma-associated ME20 antigen; M-beta

NCBI Accession #

NP_001186982.1;NP_001186983.1;NP_008859.1

Other Accession #

NP_008859.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

70255

Recommended Dilutions

WB: 1:1000

SILV Antibody (Center) (Cat# 102-12139) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SILV antibody detected the SILV protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products