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Anti-SKA2 (N-term) Antibody
Catalog #: 102-11688
Rabbit Anti-Human SKA2 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8WVK7 |
| Gene Id | 348235 |
| Gene Symbols | SKA2 |
| Protein Name / Synonyms | SKA2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SKA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SKA2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.
Specificity
Predicted Reactivity
Monkey
Other Names
SKA2; FAM33A; Spindle and kinetochore-associated protein 2; Protein FAM33A
NCBI Accession #
NP_001094065.1;NP_872426.1
Other Accession #
Q4R8E8; NP_872426.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
14188
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | SKA2 Antibody (N-term) (Cat# 102-11688) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the SKA2 antibody detected the SKA2 protein (arrow). |
 | SKA2 Antibody (N-term) (Cat# 102-11688)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SKA2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.