Anti-SMAD6 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O43541
Gene Id	4091
Gene Symbols	SMAD6
Protein Name / Synonyms	SMAD6 (Center)
Clonality	Polyclonal
Preparation	This SMAD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from the Central region of human SMAD6.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease, TGF-beta Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

SMAD6 belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling.

Specificity

Predicted Reactivity

Mouse

Other Names

SMAD6; MADH6; Mothers against decapentaplegic homolog 6; SMAD family member 6

NCBI Accession #

NP_001136333.1;NP_005576.3

Other Accession #

O35182; NP_005576.3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

53497

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	SMAD6 Antibody (Center) (Cat# 102-16473) western blot analysis in HepG2,HT29 cell line lysates (35ug/lane).This demonstrates the SMAD6 antibody detected the SMAD6 protein (arrow).
	SMAD6 Antibody (Center) (Cat# 102-16473) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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