Anti-SNX13 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9Y5W8
Gene Id	23161
Gene Symbols	SNX13
Protein Name / Synonyms	SNX13 (C-term)
Clonality	Polyclonal
Preparation	This SNX13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-807 amino acids from the C-terminal region of human SNX13.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Specificity

Predicted Reactivity

Mouse

Other Names

SNX13; KIAA0713; Sorting nexin-13; RGS domain- and PHOX domain-containing protein; RGS-PX1

NCBI Accession #

NP_055947.1

Other Accession #

Q6PHS6; NP_055947.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

112189

Recommended Dilutions

WB: 1:1000

SNX13 Antibody (C-term) (Cat# 102-11467) western blot analysis in NCI-H292,Hela cell line lysates (35ug/lane).This demonstrates the SNX13 antibody detected the SNX13 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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